Rakesh K Jain Selected Research

Neoplasm Metastasis (Metastasis)

1/2022	A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma.
11/2021	Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy.
11/2021	Author Correction: Fatty acid synthesis is required for breast cancer brain metastasis.
3/2021	Combining losartan with radiotherapy increases tumor control and inhibits lung metastases from a HER2/neu-positive orthotopic breast cancer model.
1/2021	FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS.
1/2020	Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition.
1/2019	Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer.
1/2019	Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models.
11/2018	Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood-tumor barrier disruption.
1/2018	Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2.

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Rakesh K Jain Research Topics

Disease

268	Neoplasms (Cancer) 01/2024 - 01/2002
45	Glioblastoma (Glioblastoma Multiforme) 01/2023 - 03/2002
43	Neoplasm Metastasis (Metastasis) 01/2022 - 04/2004
34	Breast Neoplasms (Breast Cancer) 01/2023 - 08/2002
26	Hypoxia (Hypoxemia) 02/2024 - 01/2005
24	Brain Neoplasms (Brain Tumor) 12/2021 - 12/2004
17	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 06/2009
15	Carcinoma (Carcinomatosis) 01/2023 - 04/2002
12	Glioma (Gliomas) 10/2018 - 03/2002
11	Edema (Dropsy) 01/2023 - 01/2007
10	Colorectal Neoplasms (Colorectal Cancer) 11/2021 - 06/2004
10	Inflammation (Inflammations) 01/2021 - 04/2004
10	Rectal Neoplasms (Rectal Cancer) 01/2010 - 02/2004
9	Hypertension (High Blood Pressure) 01/2022 - 03/2007
9	Lymphatic Metastasis 09/2015 - 06/2002
7	Necrosis 02/2024 - 05/2008
7	Pancreatic Neoplasms (Pancreatic Cancer) 01/2023 - 01/2013
7	Neurilemmoma (Schwannoma) 01/2021 - 07/2009
7	Adenocarcinoma 11/2019 - 05/2004
6	Infections 04/2024 - 11/2011
6	Disease Progression 03/2021 - 03/2002
6	Fibrosis (Cirrhosis) 01/2021 - 04/2014
5	Acoustic Neuroma (Acoustic Neurinoma) 01/2023 - 07/2009
5	Hearing Loss (Hearing Impairment) 01/2023 - 11/2015
5	Renal Cell Carcinoma (Grawitz Tumor) 01/2022 - 07/2005
5	Sarcoma (Soft Tissue Sarcoma) 11/2021 - 11/2007
5	Triple Negative Breast Neoplasms 08/2021 - 07/2011
5	Obesity 01/2018 - 01/2009
4	Granuloma 04/2024 - 02/2015
4	Tuberculosis (Tuberculoses) 04/2024 - 02/2015
4	Cholangiocarcinoma 01/2024 - 01/2017
4	Neurofibromatosis 2 (Neurofibromatosis Type II) 01/2019 - 07/2009
4	Lung Neoplasms (Lung Cancer) 07/2015 - 01/2006
4	Hyperplasia 04/2009 - 07/2004
3	Prostatic Neoplasms (Prostate Cancer) 02/2023 - 01/2012
3	Liver Neoplasms (Liver Cancer) 10/2022 - 12/2013
3	Thrombosis (Thrombus) 01/2021 - 04/2002
3	Ascites 01/2019 - 04/2009

Drug/Important Bio-Agent (IBA)

75	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023 - 03/2002
51	Biomarkers (Surrogate Marker)IBA 01/2023 - 11/2005
39	Bevacizumab (Avastin)FDA Link 04/2024 - 12/2002
21	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 11/2020 - 01/2006
19	Oxygen (Dioxygen)IBA 02/2024 - 04/2002
18	Immune Checkpoint InhibitorsIBA 01/2023 - 05/2015
18	CollagenIBA 01/2018 - 09/2002
18	cediranib (AZD2171)IBA 04/2016 - 01/2007
14	Angiogenesis InhibitorsIBA 01/2020 - 01/2005
14	Tyrosine Kinase InhibitorsIBA 01/2017 - 07/2005
11	Losartan (Cozaar)FDA LinkGeneric 04/2024 - 02/2011
11	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022 - 04/2002
9	Sorafenib (BAY 43-9006)FDA Link 10/2022 - 07/2009
9	Hyaluronic Acid (Hyaluronan)IBA 01/2018 - 09/2002
8	RNA (Ribonucleic Acid)IBA 04/2024 - 09/2011
8	Proteins (Proteins, Gene)FDA Link 01/2023 - 03/2002
8	Phosphotransferases (Kinase)IBA 10/2022 - 01/2006
8	AngiotensinsIBA 01/2022 - 01/2013
8	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 01/2020 - 02/2003
7	CytokinesIBA 12/2023 - 10/2009
7	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2023 - 11/2008
7	Angiotensin Receptor AntagonistsIBA 01/2023 - 10/2016
7	Temozolomide (Temodar)FDA LinkGeneric 01/2020 - 06/2011
7	Fluorouracil (Carac)FDA LinkGeneric 11/2019 - 10/2006
6	Monoclonal AntibodiesIBA 01/2022 - 12/2002
6	Sunitinib (Sutent)FDA Link 09/2015 - 09/2007
6	Vascular Endothelial Growth Factor CIBA 04/2009 - 06/2002
5	LigandsIBA 12/2021 - 05/2008
5	AntigensIBA 01/2020 - 09/2002
5	plerixafor FDA Link 01/2019 - 07/2010
4	Gemcitabine FDA Link 01/2024 - 06/2011
4	Neuropilin-1IBA 01/2022 - 07/2009
4	cabozantinibIBA 08/2021 - 01/2017
4	Trastuzumab (Herceptin)FDA Link 01/2020 - 11/2012
4	Oxaliplatin (Eloxatin)FDA LinkGeneric 11/2019 - 06/2011
4	Angiopoietin-1IBA 01/2018 - 04/2002
4	EnzymesIBA 01/2016 - 03/2002
4	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 01/2016 - 07/2009
4	Matrix Metalloproteinases (MMPs)IBA 04/2015 - 12/2004
4	Placenta Growth FactorIBA 11/2013 - 04/2006
4	Complementary DNA (cDNA)IBA 06/2011 - 07/2005
4	Chemokine CXCL12IBA 04/2011 - 10/2009
4	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2011 - 07/2005
4	Fibrillar CollagensIBA 06/2007 - 06/2003
3	Interleukin-6 (Interleukin 6)IBA 01/2022 - 01/2018
3	Transforming Growth Factors (Transforming Growth Factor)IBA 12/2021 - 04/2015
3	AntibodiesIBA 11/2021 - 01/2017
3	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 04/2002
3	Leucovorin (Folinic Acid)FDA Link 11/2019 - 01/2019
3	Irinotecan (Camptosar)FDA LinkGeneric 07/2019 - 08/2007
3	Protons (Proton)IBA 07/2019 - 06/2011
3	CXCR4 Receptors (CXCR4 Receptor)IBA 01/2019 - 10/2009
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2019 - 05/2008
3	Ado-Trastuzumab EmtansineIBA 01/2019 - 02/2016

Therapy/Procedure

156	Therapeutics 04/2024 - 06/2002
42	Drug Therapy (Chemotherapy) 04/2024 - 11/2003
28	Immunotherapy 12/2023 - 07/2011
24	Radiotherapy 02/2023 - 10/2006
8	Neoadjuvant Therapy 01/2022 - 10/2006
8	Aftercare (After-Treatment) 01/2020 - 06/2007
6	Lasers (Laser) 01/2018 - 01/2002
4	Chemoradiotherapy 11/2019 - 09/2007